What is the initial normal dose of levothyroxine for starting therapy?

The starting dose of levothyroxine is typically 1.6 mcg/kg of body weight per day for adults. However, the initial normal dose for individuals can vary based on factors like age, underlying health conditions, and the presence of cardiac disease. For most healthy adults who are starting on levothyroxine therapy, the standard initial dose is often set at 50 mcg. This dosage strikes a balance between providing adequate thyroid hormone replacement while minimizing the risk of overshooting the required amount, especially in patients who may be sensitive to thyroid hormone, such as older adults or those with cardiovascular conditions.

Choosing 50 mcg as the starting point, particularly in the absence of specific patient factors that necessitate a different approach, aligns well with clinical guidelines and practices. Adjustments can then be made based on subsequent TSH levels and clinical response, ensuring a tailored approach to thyroid hormone management.