Which CIN classification involves moderate dysplasia with changes in the lower 2/3 of the epithelium?

The answer is based on the classification of cervical intraepithelial neoplasia (CIN), which describes the histological grading of dysplastic changes in cervical epithelial cells. CIN 2 specifically refers to moderate dysplasia, characterized by cellular abnormalities that extend through the lower two-thirds of the epithelial layer.

This classification indicates that while there are significant dysplastic changes present, they are not yet fully developed into carcinoma. The moderate nature of CIN 2 suggests that intervention is necessary to monitor or treat the condition to prevent progression to CIN 3 or invasive carcinoma.

Understanding this classification helps in determining appropriate management strategies for women diagnosed with varying degrees of cervical dysplasia, emphasizing the importance of distinguishing CIN 2 from the other stages within the CIN classification system.